Claude Fable 5's biology refusals drop about 85%

Anthropic has retuned the biology safeguards in Claude Fable 5. In the company's own testing, refusals on biological queries fell roughly 85% across all of its products, and the model now answers a wider range of everyday health and educational questions.
What Anthropic classifies as dual-use still gets handed off to Opus 5: virology, toxicology, molecular design. That leaves Fable 5 unsuitable for professional biology research and drug development, a gap Anthropic says it plans to close through trusted access channels.
In late July, former Anthropic engineer Adi Baradwaj publicly accused the company of the opposite: watering down safeguards to win corporate contracts.
Related stories
- Former Anthropic engineer says the company loosened safeguards for enterprise deals
- Anthropic releases System Card for Claude Sonnet 5
- Anthropic plans public release of Mythos models
- Anthropic will bill again for requests its safeguards block
- Opus 5.5 matches Fable 5.1 on most work for less money
- Anthropic's 225 bug finds, one attack in the wild
Comments
No comments yet. Be the first.
Join the conversation
Sign in with Google to leave a comment. Your name and avatar come from your Google profile, and the comment appears after moderation.
